Maritime halophyte species from southern Portugal as sources of bioactive molecules.

Rodrigues, Maria João; Gangadhar, Katkam N; Vizetto-Duarte, Catarina; Wubshet, Sileshi G; Nyberg, Nils T; Luísa Barreira; João Varela; Luísa Custódio; Alrokayan, Salman A; Mouffouk, Fouzi; Abu-Salah, Khalid M; Ben-Hamadou, Radhouan; João Varela

XtremeBio

Short Title

XtremeBio

Description

We are engaged in the smart and sustainable exploitation of marine resources, including micro- and macroalgae, seagrasses, marine invertebrates and also coastal plants (halophytes).

Coordinator

Luísa Custódio

Organiza

Main

Our research is divided in 5 sub areas: XtremeFoods (for human nutrition); XtremePharma (for pharmaceutical uses), XtremeVet (for veterinary aplications); XtremeBeauty (for cosmetics) and XtremeCrops (Production of selected species).

Most relevant expected contributions of this research team includes the development and optimization of innovative commercial products incorporating active extracts from selected marine species, to be used in different commercial areas, and of sustainable cultivation technologies, such as in vitro techniques, greenhouse cultivation and IMTA systems, aiming the production of biomass and ingredients for commercial purposes.

News

NEW POSITION: Luísa Margarida Batista Custódio

Congrats Doctor Catarina Pereira

New on Board: Viana Loaiza

Members

Enroll

Table view

Coordinator	Position
Luísa Custódio	Senior Researcher

Name	Position
Catarina Guerreiro Pereira	Investigador
Cristiana do Couto Pereira Maia	PhD Student
Eliana Fernandes	PhD Student
Maria João da Silva Rodrigues	Postdoc
Marta Oliveira

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Catarina Guerreiro Pereira

Position:

Investigador

Cristiana do Couto Pereira Maia

Position:

PhD Student

Eliana Fernandes

Position:

PhD Student

Maria João da Silva Rodrigues

Position:

Postdoc

Marta Oliveira

Position:

Gallery

Publications

All Publications


Rodrigues MJoão, Slusarczyk S, Pecio Ł, et al. In vitro and in silico approaches to appraise Polygonum maritimum L. as a source of innovative products with anti-ageing potential. Industrial Crops and Products. 2018;111:391 - 399. doi:10.1016/j.indcrop.2017.10.046 Read more about In vitro and in silico approaches to appraise Polygonum maritimum L. as a source of innovative products with anti-ageing potential Google Scholar DOI
Pereira CGuerreiro, Barreira L, Bijttebier S, et al. Chemical profiling of infusions and decoctions of Helichrysum italicum subsp. picardii by UHPLC-PDA-MS and in vitro biological activities comparatively with green tea ( Camellia sinensis ) and rooibos tisane ( Aspalathus linearis ). Journal of Pharmaceutical and Biomedical Analysis. 2017;145:593 - 603. doi:10.1016/j.jpba.2017.07.007 Read more about Chemical profiling of infusions and decoctions of Helichrysum italicum subsp. picardii by UHPLC-PDA-MS and in vitro biological activities comparatively with green tea ( Camellia sinensis ) and rooibos tisane ( Aspalathus linearis ) Google Scholar DOI
Oliveira M, Rodrigues MJoão, Pereira C, et al. First report of the in vitro antileishmanial properties of extremophile plants from the Algarve Coast. Natural Product Research. 2017:1 - 5. doi:10.1080/14786419.2017.1326489 Read more about First report of the in vitro antileishmanial properties of extremophile plants from the Algarve Coast Google Scholar DOI
Rocha MI, Rodrigues MJ, Pereira C, et al. Biochemical profile and in vitro neuroprotective properties of Carpobrotus edulis L., a medicinal and edible halophyte native to the coast of South Africa. South African Journal of Botany. 2017;111:222 - 231. doi:10.1016/j.sajb.2017.03.036 Read more about Biochemical profile and in vitro neuroprotective properties of Carpobrotus edulis L., a medicinal and edible halophyte native to the coast of South Africa Google Scholar DOI
Rodrigues MJoão, Neves V, Martins A, et al. In vitro antioxidant and anti-inflammatory properties of Limonium algarvense flowers' infusions and decoctions: A comparison with green tea (Camellia sinensis). Food Chem. 2016;200:322-9. doi:10.1016/j.foodchem.2016.01.048 Read more about In vitro antioxidant and anti-inflammatory properties of Limonium algarvense flowers' infusions and decoctions: A comparison with green tea (Camellia sinensis). Google Scholar PubMed DOI
Lopes A, Rodrigues MJoão, Pereira C, et al. Natural products from extreme marine environments: Searching for potential industrial uses within extremophile plants. Industrial Crops and Products. 2016;94:299 - 307. doi:10.1016/j.indcrop.2016.08.040 Read more about Natural products from extreme marine environments: Searching for potential industrial uses within extremophile plants Google Scholar DOI
Ismael A, Henriques MSC, Marques C, et al. Exploring saccharinate-tetrazoles as selective Cu(. RSC Adv. 2016;6(75):71628 - 71637. doi:10.1039/C6RA15051A Read more about Exploring saccharinate-tetrazoles as selective Cu( Google Scholar DOI
Pereira H, Custódio L, Rodrigues MJ, et al. Profiling of antioxidant potential and phytoconstituents of Plantago coronopus. Brazilian Journal of Biology. 2016;(ahead). doi:10.1590/1519-6984.02416 Read more about Profiling of antioxidant potential and phytoconstituents of Plantago coronopus Google Scholar DOI
Oliveira M, Junior PAdemar Sal, Rodrigues MJoão, et al. Unlocking the in vitro anti-Trypanosoma cruzi activity of halophyte plants from the southern Portugal. Asian Pac J Trop Med. 2016;9(8):735-41. doi:10.1016/j.apjtm.2016.06.015 Read more about Unlocking the in vitro anti-Trypanosoma cruzi activity of halophyte plants from the southern Portugal. Google Scholar PubMed DOI
Custódio L, Laukaityte S, Engelen AH, et al. A comparative evaluation of biological activities and bioactive compounds of the seagrasses Zostera marina and Zostera noltei from southern Portugal. Natural Product Research. 2016;30(6):724 - 728. doi:10.1080/14786419.2015.1040791 Read more about A comparative evaluation of biological activities and bioactive compounds of the seagrasses Zostera marina and Zostera noltei from southern Portugal Google Scholar DOI
Grosso C, Cardoso ALúcia, Lemos A, et al. Novel approach to bis(indolyl)methanes: de novo synthesis of 1-hydroxyiminomethyl derivatives with anti-cancer properties. Eur J Med Chem. 2015;93:9-15. doi:10.1016/j.ejmech.2015.01.050 Read more about Novel approach to bis(indolyl)methanes: de novo synthesis of 1-hydroxyiminomethyl derivatives with anti-cancer properties. Google Scholar PubMed DOI
Cravo A, Fernandes D, Damião T, Pereira C, Reis MP. Determining the footprint of sewage discharges in a coastal lagoon in South-Western Europe. Mar Pollut Bull. 2015;96(1-2):197-209. doi:10.1016/j.marpolbul.2015.05.029 Read more about Determining the footprint of sewage discharges in a coastal lagoon in South-Western Europe. Google Scholar PubMed DOI
Pereira H, Custódio L, Rodrigues MJoão, et al. Biological Activities and Chemical Composition of Methanolic Extracts of Selected Autochthonous Microalgae Strains from the Red Sea. Mar Drugs. 2015;13(6):3531-49. doi:10.3390/md13063531 Read more about Biological Activities and Chemical Composition of Methanolic Extracts of Selected Autochthonous Microalgae Strains from the Red Sea. Google Scholar PubMed DOI
Rodrigues MJoão, Gangadhar KN, Vizetto-Duarte C, et al. Maritime halophyte species from southern Portugal as sources of bioactive molecules. Mar Drugs. 2014;12(4):2228-44. doi:10.3390/md12042228 Read more about Maritime halophyte species from southern Portugal as sources of bioactive molecules. Google Scholar PubMed DOI

Projects

	Title	Coordinator	Time frame	Funding	CCMAR	All
GreenValue	Exploring salt tolerant plants as sources of innovative food additives	Luísa Custódio	03/15/2021 to 03/14/2024	FCT	203,581.45k€
SaltyCrops	Exploring Sarcocornia as a halophyte biofilter for mariculture effluents and a source for lucrative foods and specialty biochemical	Luísa Custódio	06/15/2020 to 06/14/2022	FCT		99,99k€
XtremeAquaCrops	Implementation and optimization of an integrated multitrophic aquaculture (IMTA) system for marine fish and aquaponic extremophile medicinal halophytes production	Luísa Custódio	09/01/2019 to 08/31/2021	Fundo Azul		199,41k€
GreenVet	GreenVet: Unravelling the potential of marine halophyte plants as sources of innovative products with veterinary uses	Luísa Custódio	09/01/2018 to 08/31/2021	FCT	215.51k€	238,88k€
SmartBeauty	Smart valorisation and sustainable use of natural resources from coastal areas of Portugal and France in the cosmetic industry	Luísa Custódio

	Title	Coordinator	Time frame	Funding	CCMAR
ManaCruzi	Marine Natural Products Against T. cruzi		01/01/2014 to 12/31/2015	FCT
XTREMEBIO	Halófitas: um recurso precioso de elementos nutricionais e compostos bioactivos	Luísa Custódio	05/01/2013 to 08/31/2015	FCT	135.21k€
SEABIOMED	Organismos fotossintéticos marinhos da costa Algarvia com aplicações biomédicas	Luísa Custódio	01/04/2010 to 04/30/2013	FCT	159.02k€

	Title	Coordinator	Time frame	Funding	CCMAR	All
HaloFarMs	Development and Optimization of Halophyte-based Farming systems in salt-affected Mediterranean Soils		10/01/2020			1.000,00k€

Events

Type of Event

Seminar

The GreenVet project: unravelling the use of salt tolerant species in veterinary

Room 2.31 I Building 7 I Campus Gambelas

April 24, 2019

Sala 2.31 I Edifício 7 I Campus Gambelas

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