Phytochemical profile, antioxidant and cytotoxic activities of the carob tree (Ceratonia siliqua L.) germ flour extracts.

Luísa Custódio; Escapa, Ana Luísa; Fernandes, Eliana; Fajardo, Alba; Aligué, Rosa; Alberício, Fernando; Neng, Nuno; Nogueira, José Manuel Florêncio; Romano, Anabela; Mouffouk, Fouzi; Abu-Salah, Khalid M; Ben-Hamadou, Radhouan; João Varela

XtremeBio

Short Title

XtremeBio

Description

We are engaged in the smart and sustainable exploitation of marine resources, including micro- and macroalgae, seagrasses, marine invertebrates and also coastal plants (halophytes).

Coordinator

Luísa Custódio

Organiza

Main

Our research is divided in 5 sub areas: XtremeFoods (for human nutrition); XtremePharma (for pharmaceutical uses), XtremeVet (for veterinary aplications); XtremeBeauty (for cosmetics) and XtremeCrops (Production of selected species).

Most relevant expected contributions of this research team includes the development and optimization of innovative commercial products incorporating active extracts from selected marine species, to be used in different commercial areas, and of sustainable cultivation technologies, such as in vitro techniques, greenhouse cultivation and IMTA systems, aiming the production of biomass and ingredients for commercial purposes.

News

NEW POSITION: Luísa Margarida Batista Custódio

Members

Enroll

Membros atuais (ver em tabela)

Coordinator	Posição
Luísa Custódio	Senior Researcher

Name	Posição
Catarina Guerreiro Pereira	PhD Student
Cristiana do Couto Pereira Maia	PhD Student
Luísa Custódio	Senior Researcher
Maria João da Silva Rodrigues	PhD Student
Marta Oliveira

Membros atuais (ver em grelha)

Catarina Guerreiro Pereira

Posição:

PhD Student

Cristiana do Couto Pereira Maia

Posição:

PhD Student

Luísa Custódio

Posição:

Senior Researcher

Maria João da Silva Rodrigues

Posição:

PhD Student

Marta Oliveira

Posição:

Galeria

Publications

All Publications


Rodrigues MJoão, Slusarczyk S, Pecio Ł, et al. In vitro and in silico approaches to appraise Polygonum maritimum L. as a source of innovative products with anti-ageing potential. Industrial Crops and Products. 2018;111:391 - 399. doi:10.1016/j.indcrop.2017.10.046 Ler mais acerca de In vitro and in silico approaches to appraise Polygonum maritimum L. as a source of innovative products with anti-ageing potential Google Scholar DOI
Rocha MI, Rodrigues MJ, Pereira C, et al. Biochemical profile and in vitro neuroprotective properties of Carpobrotus edulis L., a medicinal and edible halophyte native to the coast of South Africa. South African Journal of Botany. 2017;111:222 - 231. doi:10.1016/j.sajb.2017.03.036 Ler mais acerca de Biochemical profile and in vitro neuroprotective properties of Carpobrotus edulis L., a medicinal and edible halophyte native to the coast of South Africa Google Scholar DOI
Pereira CGuerreiro, Barreira L, Bijttebier S, et al. Chemical profiling of infusions and decoctions of Helichrysum italicum subsp. picardii by UHPLC-PDA-MS and in vitro biological activities comparatively with green tea ( Camellia sinensis ) and rooibos tisane ( Aspalathus linearis ). Journal of Pharmaceutical and Biomedical Analysis. 2017;145:593 - 603. doi:10.1016/j.jpba.2017.07.007 Ler mais acerca de Chemical profiling of infusions and decoctions of Helichrysum italicum subsp. picardii by UHPLC-PDA-MS and in vitro biological activities comparatively with green tea ( Camellia sinensis ) and rooibos tisane ( Aspalathus linearis ) Google Scholar DOI
Oliveira M, Rodrigues MJoão, Pereira C, et al. First report of the in vitro antileishmanial properties of extremophile plants from the Algarve Coast. Natural Product Research. 2017:1 - 5. doi:10.1080/14786419.2017.1326489 Ler mais acerca de First report of the in vitro antileishmanial properties of extremophile plants from the Algarve Coast Google Scholar DOI
Oliveira M, Junior PAdemar Sal, Rodrigues MJoão, et al. Unlocking the in vitro anti-Trypanosoma cruzi activity of halophyte plants from the southern Portugal. Asian Pac J Trop Med. 2016;9(8):735-41. doi:10.1016/j.apjtm.2016.06.015 Ler mais acerca de Unlocking the in vitro anti-Trypanosoma cruzi activity of halophyte plants from the southern Portugal. Google Scholar PubMed DOI
Custódio L, Laukaityte S, Engelen AH, et al. A comparative evaluation of biological activities and bioactive compounds of the seagrasses Zostera marina and Zostera noltei from southern Portugal. Natural Product Research. 2016;30(6):724 - 728. doi:10.1080/14786419.2015.1040791 Ler mais acerca de A comparative evaluation of biological activities and bioactive compounds of the seagrasses Zostera marina and Zostera noltei from southern Portugal Google Scholar DOI
Pereira H, Custódio L, Rodrigues MJ, et al. Profiling of antioxidant potential and phytoconstituents of Plantago coronopus. Brazilian Journal of Biology. 2016;(ahead). doi:10.1590/1519-6984.02416 Ler mais acerca de Profiling of antioxidant potential and phytoconstituents of Plantago coronopus Google Scholar DOI
Pereira H, Gangadhar KN, Schulze PSC, et al. Isolation of a euryhaline microalgal strain, Tetraselmis sp. CTP4, as a robust feedstock for biodiesel production. Scientific Reports. 2016;6:35663. doi:10.1038/srep35663 Ler mais acerca de Isolation of a euryhaline microalgal strain, Tetraselmis sp. CTP4, as a robust feedstock for biodiesel production Google Scholar DOI
Gangadhar KN, Pereira H, Diogo HP, et al. Assessment and comparison of the properties of biodiesel synthesized from three different types of wet microalgal biomass. Journal of Applied Phycology. 2016;28(3):1571 - 1578. doi:10.1007/s10811-015-0683-5 Ler mais acerca de Assessment and comparison of the properties of biodiesel synthesized from three different types of wet microalgal biomass Google Scholar DOI
Ismael A, Henriques MSC, Marques C, et al. Exploring saccharinate-tetrazoles as selective Cu(. RSC Adv. 2016;6(75):71628 - 71637. doi:10.1039/C6RA15051A Ler mais acerca de Exploring saccharinate-tetrazoles as selective Cu( Google Scholar DOI
Rodrigues MJoão, Neves V, Martins A, et al. In vitro antioxidant and anti-inflammatory properties of Limonium algarvense flowers' infusions and decoctions: A comparison with green tea (Camellia sinensis). Food Chem. 2016;200:322-9. doi:10.1016/j.foodchem.2016.01.048 Ler mais acerca de In vitro antioxidant and anti-inflammatory properties of Limonium algarvense flowers' infusions and decoctions: A comparison with green tea (Camellia sinensis). Google Scholar PubMed DOI
Lopes A, Rodrigues MJoão, Pereira C, et al. Natural products from extreme marine environments: Searching for potential industrial uses within extremophile plants. Industrial Crops and Products. 2016;94:299 - 307. doi:10.1016/j.indcrop.2016.08.040 Ler mais acerca de Natural products from extreme marine environments: Searching for potential industrial uses within extremophile plants Google Scholar DOI
Vizetto-Duarte C, Pereira H, de Sousa CBruno, et al. Fatty acid profile of different species of algae of the Cystoseira genus: a nutraceutical perspective. Nat Prod Res. 2015;29(13):1264-70. doi:10.1080/14786419.2014.992343 Ler mais acerca de Fatty acid profile of different species of algae of the Cystoseira genus: a nutraceutical perspective. Google Scholar PubMed DOI
Grosso C, Cardoso ALúcia, Lemos A, et al. Novel approach to bis(indolyl)methanes: de novo synthesis of 1-hydroxyiminomethyl derivatives with anti-cancer properties. Eur J Med Chem. 2015;93:9-15. doi:10.1016/j.ejmech.2015.01.050 Ler mais acerca de Novel approach to bis(indolyl)methanes: de novo synthesis of 1-hydroxyiminomethyl derivatives with anti-cancer properties. Google Scholar PubMed DOI
Cravo A, Fernandes D, Damião T, Pereira C, Reis MP. Determining the footprint of sewage discharges in a coastal lagoon in South-Western Europe. Mar Pollut Bull. 2015;96(1-2):197-209. doi:10.1016/j.marpolbul.2015.05.029 Ler mais acerca de Determining the footprint of sewage discharges in a coastal lagoon in South-Western Europe. Google Scholar PubMed DOI
Pereira H, Custódio L, Rodrigues MJoão, et al. Biological Activities and Chemical Composition of Methanolic Extracts of Selected Autochthonous Microalgae Strains from the Red Sea. Mar Drugs. 2015;13(6):3531-49. doi:10.3390/md13063531 Ler mais acerca de Biological Activities and Chemical Composition of Methanolic Extracts of Selected Autochthonous Microalgae Strains from the Red Sea. Google Scholar PubMed DOI
Rodrigues MJoão, Gangadhar KN, Vizetto-Duarte C, et al. Maritime halophyte species from southern Portugal as sources of bioactive molecules. Mar Drugs. 2014;12(4):2228-44. doi:10.3390/md12042228 Ler mais acerca de Maritime halophyte species from southern Portugal as sources of bioactive molecules. Google Scholar PubMed DOI
Martins DAlves, Custódio L, Barreira L, et al. Alternative sources of n-3 long-chain polyunsaturated fatty acids in marine microalgae. Mar Drugs. 2013;11(7):2259-81. doi:10.3390/md11072259 Ler mais acerca de Alternative sources of n-3 long-chain polyunsaturated fatty acids in marine microalgae. Google Scholar PubMed DOI
Pereira H, Barreira L, Figueiredo F, et al. Polyunsaturated Fatty acids of marine macroalgae: potential for nutritional and pharmaceutical applications. Mar Drugs. 2012;10(9):1920-35. doi:10.3390/md10091920 Ler mais acerca de Polyunsaturated Fatty acids of marine macroalgae: potential for nutritional and pharmaceutical applications. Google Scholar PubMed DOI
Custodio L, Fernandes E, Escapa AL, et al. Antioxidant and cytotoxic activities of carob tree fruit pulps are strongly influenced by gender and cultivar. J Agric Food Chem. 2011;59(13):7005-12. doi:10.1021/jf200838f Ler mais acerca de Antioxidant and cytotoxic activities of carob tree fruit pulps are strongly influenced by gender and cultivar. Google Scholar PubMed DOI
Pereira H, Barreira L, Mozes A, et al. Microplate-based high throughput screening procedure for the isolation of lipid-rich marine microalgae. Biotechnol Biofuels. 2011;4(1):61. doi:10.1186/1754-6834-4-61 Ler mais acerca de Microplate-based high throughput screening procedure for the isolation of lipid-rich marine microalgae. Google Scholar PubMed DOI
Custódio L, Escapa ALuísa, Fernandes E, et al. Phytochemical profile, antioxidant and cytotoxic activities of the carob tree (Ceratonia siliqua L.) germ flour extracts. Plant Foods Hum Nutr. 2011;66(1):78-84. doi:10.1007/s11130-011-0214-8 Ler mais acerca de Phytochemical profile, antioxidant and cytotoxic activities of the carob tree (Ceratonia siliqua L.) germ flour extracts. Google Scholar PubMed DOI

Projects

Activities

Activity type

Seminário

The GreenVet project: unravelling the use of salt tolerant species in veterinary

Sala 2.31 I Edifício 7 I Campus Gambelas

Qua, 24/04/2019

Sala 2.31 I Edifício 7 I Campus Gambelas

News

NEW POSITION: Luísa Margarida Batista Custódio

Luísa Custódio trabalhou anteriormente no CCMAR como investigadora auxiliar e juntou-se ao grupo XtremeBio. Parabéns à nova posição Luísa!