Evolution of matrix and bone  gamma-carboxyglutamic acid proteins in vertebrates

Vincent Laizé; Martel, Paulo; Carla SB Viegas; Price, Paul A.; M. Leonor Cancela; Bargelloni, Luca; Boudry, Pierre; Boulo, Viviane; Dias, Jorge; Huvet, Arnaud; Vincent Laizé; Lapègue, Sylvie; Leite, Ricardo; Mira, Sara; Nielsen, Einar E.; Planas, Josep V.; Roher, Nerea; Sarropoulou, Elena; Volckaert, Filip A.M.

Vincent Laizé

Position

Senior Researcher

Academic Degree

Doutoramento

Group Leader

Comparative, Adaptive and Functional Skeletal Biology

Group

Comparative, Adaptive and Functional Skeletal Biology

Based at

Faro, Gambelas Campus, UAlg

Office Nr

2.76

Phone Nr

+351 289800057

Extension

7057

vlaize@ualg.pt

Keywords

zebrafish, extracellular matrix mineralization, bone development, marine biotechnology, osteotoxicity, gene regulation, regeneration

ORCID ID

ResearchGate

Scopus

Organiza

Main Info

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For more information see also the webpage of the BIOSKEL lab at http://bioskel.ccmar.ualg.pt/

Projects

Projects Coordination

	Title	Coordinator	Start	End	Funding	Budget CCMAR	Budget Total
DEEPBONE	DEEPBONE - Biologia do osso de peixes de profundidade	Vincent Laizé	01/2012	06/2015	FCT	109k€	109k€
AQUATOX	Avaliação da toxidade óssea de poluentes aquáticos.	Vincent Laizé	07/2011	12/2014	FCT	113k€	113k€
SaMGP	Effect of extracellular calcium on MGP gene expression	Vincent Laizé	03/2003	03/2006		100k€	100k€

Projects Membership

	Title	Coordinator	Start	End	Funding	Budget CCMAR	Budget Total
ULTRAFISH	ULTRAFISH - Utilização de ultrasons na optimização da nutrição embrionária de peixes: programação nutricional do potencial de crescimento e capacidades metabólicas em juvenis.	Jorge Dias	03/2010	08/2013	FCT	190k€
SPECIAL_K	Efeitos da suplementação nutricional em vitamina K no crescimento e desenvolvimento esquelético de peixes teleósteos	Paulo Jorge Travessa Gavaia	02/2010	07/2013	FCT	195k€	195107k€

Activities

ATT: Using Zebrafish as a model in Biomedicine and study of human diseases - 3rd Edition

21st April 2017 Organization: CCMAR Location: Universidade do Algarve - Campus de Gambelas (limited places)

Sex, 21/04/2017

CCMAR - Universidade do Algarve - Campus de Gambelas (Faro)

News

Especialistas discutem esqueleto e problemas ósseos esta semana

O CCMAR organiza esta semana a 5ª edição da Conferência “Interdisciplinary Approaches in Fish Skeletal Biology (IAFSB)” em Tavira, Portugal.

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Neste evento, foram apresentados o papel das empresas produtoras de microalgas, novas estratégias de produção de microalgas desenvolvidas no LNEG, o conceito de biorrefinaria de biomassa algal e duas mesas redondas.

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Publications

Year of Publication
2019	Navarro-Guillén C, Dias J, Rocha F, et al. Does a ghrelin stimulus during zebrafish embryonic stage modulate its performance on the long-term?. Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 2019;228:1 - 8. doi:10.1016/j.cbpa.2018.10.019 Ler mais acerca de Does a ghrelin stimulus during zebrafish embryonic stage modulate its performance on the long-term? Google Scholar DOI
2019	Tarasco M, Cardeira J, Viegas M, et al. Anti-osteogenic activity of cadmium in zebrafish. Fishes. 2019;4(1):11. doi:10.3390/fishes4010011 Ler mais acerca de Anti-osteogenic activity of cadmium in zebrafish Google Scholar DOI
2018	Carson MA, Nelson J, M. Cancela L, et al. Screening for osteogenic activity in extracts from Irish marine organisms: The potential of Ceramium pallidum. Cray JJ, ed. PLOS ONE. 2018;13(11):e0207303. doi:10.1371/journal.pone.0207303.s008 Ler mais acerca de Screening for osteogenic activity in extracts from Irish marine organisms: The potential of Ceramium pallidum Google Scholar DOI
2018	Fernández I, Gavaia P, Laizé V, M. Cancela L. Fish as a model to assess chemical toxicity in bone. Aquatic Toxicology. 2018;194:208 - 226. doi:10.1016/j.aquatox.2017.11.015 Ler mais acerca de Fish as a model to assess chemical toxicity in bone Google Scholar DOI
2018	Rosa J, Cox CJ, M. Cancela L, Laizé V. Identification of a fish short-chain dehydrogenase/reductase associated with bone metabolism. Gene. 2018;645:137 - 145. doi:10.1016/j.gene.2017.12.021 Ler mais acerca de Identification of a fish short-chain dehydrogenase/reductase associated with bone metabolism Google Scholar DOI
2018	Cardeira J, Laizé V, Martins G, M. Cancela L, Gavaia P. An overview on the teleost bone mechanophysiology. Journal of Applied Ichthyology. 2018. doi:10.1111/jai.13661 Ler mais acerca de An overview on the teleost bone mechanophysiology Google Scholar DOI
2018	Carson MA, Nelson J, M. Cancela L, et al. Red algal extracts from Plocamium lyngbyanum and Ceramium secundatum stimulate osteogenic activities in vitro and bone growth in zebrafish larvae. Scientific Reports. 2018;8(1). doi:10.1038/s41598-018-26024-0 Ler mais acerca de Red algal extracts from Plocamium lyngbyanum and Ceramium secundatum stimulate osteogenic activities in vitro and bone growth in zebrafish larvae Google Scholar DOI
2018	Laizé V, Gavaia P, Tarasco M, et al. Osteotoxicity of 3-methylcholanthrene in fish. Ecotoxicology and Environmental Safety. 2018;161:721 - 728. doi:10.1016/j.ecoenv.2018.06.035 Ler mais acerca de Osteotoxicity of 3-methylcholanthrene in fish Google Scholar DOI
2017	Tarasco M, Laizé V, Cardeira J, M. Cancela L, Gavaia P. The zebrafish operculum: A powerful system to assess osteogenic bioactivities of molecules with pharmacological and toxicological relevance. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology. 2017;197:45 - 52. doi:10.1016/j.cbpc.2017.04.006 Ler mais acerca de The zebrafish operculum: A powerful system to assess osteogenic bioactivities of molecules with pharmacological and toxicological relevance Google Scholar DOI
2017	Marques C, Roberto VP, Granadeiro L, et al. The xenobiotic sensor PXR in a marine flatfish species ( Solea senegalensis ): Gene expression patterns and its regulation under different physiological conditions. Marine Environmental Research. 2017;130:187-199. doi:10.1016/j.marenvres.2017.07.021 Ler mais acerca de The xenobiotic sensor PXR in a marine flatfish species ( Solea senegalensis ): Gene expression patterns and its regulation under different physiological conditions Google Scholar DOI
2016	Cardeira J, Gavaia P, Fernández I, et al. Quantitative assessment of the regenerative and mineralogenic performances of the zebrafish caudal fin. Scientific Reports. 2016;6:39191. doi:10.1038/srep39191 Ler mais acerca de Quantitative assessment of the regenerative and mineralogenic performances of the zebrafish caudal fin Google Scholar DOI
2014	Laizé V, Gavaia P, M. Cancela L. Fish: a suitable system to model human bone disorders and discover drugs with osteogenic or osteotoxic activities. Drug Discovery Today: Disease Models. 2014;13:29-37. doi:10.1016/j.ddmod.2014.08.001 Ler mais acerca de Fish: a suitable system to model human bone disorders and discover drugs with osteogenic or osteotoxic activities Google Scholar DOI
2012	Viegas MN, Dias J, M. Cancela L, Laizé V. Polyunsaturated fatty acids regulate cell proliferation, extracellular matrix mineralization and gene expression in a gilthead seabream skeletal cell line. Journal of Applied Ichthyology. 2012;28(3):427-432. doi:10.1111/j.1439-0426.2012.01994.x Ler mais acerca de Polyunsaturated fatty acids regulate cell proliferation, extracellular matrix mineralization and gene expression in a gilthead seabream skeletal cell line Google Scholar DOI
2010	Rosa J, Tiago DM, Dias J, M. Cancela L, Laizé V. Serum-specific stimulation of proliferation and mineralization of fish bone-derived cells. Journal of Applied Ichthyology. 2010;26(2):251 - 256. doi:10.1111/jai.2010.26.issue-210.1111/j.1439-0426.2010.01414.x Ler mais acerca de Serum-specific stimulation of proliferation and mineralization of fish bone-derived cells Google Scholar DOI
2010	Rafael MS, Marques CL, Parameswaran V, M. Cancela L, Laizé V. Fish bone-derived cell lines: an alternative in vitro cell system to study bone biology. Journal of Applied Ichthyology. 2010;26(2):230-234. doi:10.1111/jai.2010.26.issue-210.1111/j.1439-0426.2010.01411.x Ler mais acerca de Fish bone-derived cell lines: an alternative in vitro cell system to study bone biology Google Scholar DOI
2010	M. Cancela L, Bargelloni L, Boudry P, et al. Genomic approaches in aquaculture and fisheries. In: J. Cock M, Tessmar-Raible K, Boyen C, Viard F, eds. Introduction To Marine Genomics. Introduction to marine genomics. Dordrecht: Springer Netherlands; 2010:213-286. doi:10.1007/978-90-481-8639-610.1007/978-90-481-8639-6_7 Ler mais acerca de Genomic approaches in aquaculture and fisheries Google Scholar DOI
2006	Laizé V, Viegas CSB, Price PA, M. Cancela L. Identification of an osteocalcin isoform in fish with a large acidic prodomain. Journal of Biological Chemistry. 2006;281(22):15037-15043. doi:10.1074/jbc.M600373200 Ler mais acerca de Identification of an osteocalcin isoform in fish with a large acidic prodomain Google Scholar DOI
2006	Braga D, Laizé V, Tiago DM, M. Cancela L. Enhanced DNA transfer into fish bone cells using polyethylenimine. Molecular Biotechnology. 2006;34(1):51-54. doi:10.1385/MB:34:110.1385/MB:34:1:51 Ler mais acerca de Enhanced DNA transfer into fish bone cells using polyethylenimine Google Scholar DOI
2005	Fonseca VG, Lago-Lestón A, Laizé V, M. Cancela L. Rapid identification of differentially expressed genes by in situ screening of bacteria. Molecular Biotechnology. 2005;30(2):163-166. doi:10.1385/MB:30:210.1385/MB:30:2:163 Ler mais acerca de Rapid identification of differentially expressed genes by in situ screening of bacteria Google Scholar DOI
2005	Laizé V, Martel P, Viegas CSB, Price PA, M. Cancela L. Evolution of matrix and bone gamma-carboxyglutamic acid proteins in vertebrates. Journal of Biological Chemistry. 2005;280(29):26659-26668. doi:10.1074/jbc.M500257200 Ler mais acerca de Evolution of matrix and bone gamma-carboxyglutamic acid proteins in vertebrates Google Scholar DOI