|Title||The Davydov/Scott model for energy storage and transport in proteins.|
|Publication Type||Journal Article|
|Year of Publication||2009|
|Journal||J Biol Phys|
|Date Published||2009 Feb|
The current status of the Davydov/Scott model for energy transfer in proteins is reviewed. After a brief introduction to the theoretical framework and to the basic results, the problems of finite temperature dynamics and of the full quantum and mixed quantum-classical approximations are described, as well as recent results obtained within each of these approximations. A short survey of experimental evidence in support of the Davydov/Scott model is made and absorption spectra are calculated that show the same temperature dependence as that measured in crystalline acetanilide. Future applications of the Davydov/Scott model to protein folding and function and to misfolding diseases are outlined.
|Alternate Journal||J Biol Phys|
|PubMed Central ID||PMC2660397|