Comparative study of family 2 GPCRs in Fugu rubripes. | - CCMAR -

Journal Article

TitleComparative study of family 2 GPCRs in Fugu rubripes.
Publication TypeJournal Article
AuthorsCardoso, JCR, Power, DM, Clark, M
Year of Publication2005
JournalAnn N Y Acad Sci
Volume1040
Date Published2005 Apr
Pagination257-60
ISSN0077-8923
KeywordsAnimals, Phylogeny, Receptors, G-Protein-Coupled, Takifugu
Abstract

In this study, members of family 2 GPCRs, one of the largest families of receptors in vertebrates, were isolated and characterized in the genome of the Japanese pufferfish, Fugu rubripes, and compared with the orthologous genes in other vertebrates. Phylogenetic analysis carried out with all vertebrate family 2 GPCR members indicated that CALR/CGRPR and CRF are the most divergent receptor group within this family and that the remaining members appear to originate from a common ancestral gene precursor.

DOI10.1196/annals.1327.037
Sapientia

http://www.ncbi.nlm.nih.gov/pubmed/15891037?dopt=Abstract

Alternate JournalAnn. N. Y. Acad. Sci.
PubMed ID15891037