Publications | - CCMAR -
Found 32 results
Filters: Author is Simes, Dina C.  [Clear All Filters]
2019
Viegas CSB, Simes DC. A dual role for GRP in cardiovascular disease. Aging. 2019;11(5):1323 - 1324. doi:10.18632/aging.v11i510.18632/aging.101851
2018
Viegas CSB, Santos L, Macedo AL, et al. Chronic Kidney Disease Circulating Calciprotein Particles and Extracellular Vesicles Promote Vascular Calcification. Arteriosclerosis, Thrombosis, and Vascular Biology. 2018;38(3):575 - 587. doi:10.1161/ATVBAHA.117.310578
Viegas CSB, Simes DC. Immunity And Inflammation In Health And Disease: Inflammation And Calcification In The Vascular Tree; Insights Into Atherosclerosis. Elsevier; 2018:189 - 201. doi:10.1016/B978-0-12-805417-8.00015-9
Viegas CSB, Macedo AL, Matos AA, et al. Translational Research and Innovation in Human and Health Science: Gla-rich protein, a vitamin K-dependent protein involved in inflammation and calcification-related diseases. Annals of Medicine. 2018;50(sup1):S1 - S9. doi:10.1080/07853890.2018.1427452
Willems BA, Furmanik M, Caron MMJ, et al. Ucma/GRP inhibits phosphate-induced vascular smooth muscle cell calcification via SMAD-dependent BMP signalling. Scientific Reports. 2018;8(1). doi:10.1038/s41598-018-23353-y
2017
Morais R, Viegas CSB, Simes DC, Matos APA, Macedo AL. Application of TEM techniques for the study of vascular calcification: Monitoring extracellular vesicles and nanogold immunodetection of fetuin-A, GRP, and CD9. Ultrastructural Pathology. 2017;41(1):130 - 132. doi:10.1080/01913123.2016.1272670
Viegas CSB, Macedo AL, Morais R, et al. Dysregulated fetuin–mineral complexes are linked to vascular calcification in chronic kidney disease: The role of Gla-rich protein. Ultrastructural Pathology. 2017;41(1):78 - 80. doi:10.1080/01913123.2016.1269490
Viegas CSB, Costa RM, Santos L, et al. Gla-rich protein function as an anti-inflammatory agent in monocytes/macrophages: Implications for calcification-related chronic inflammatory diseases. . de Frutos PGarcia, ed. PLOS ONE. 2017;12(5):e0177829.
2016
Macedo AL, Viegas CSB, Matos APA, Simes DC. Extracellular Vesicles and Circulating Fetuin-Mineral Complexes in Vascular Calcification; Studies by EM Techniques. Microscopy and Microanalysis. 2016;22(S4):16 - 17. doi:10.1017/S1431927616000271
Viegas CSB, Simes DC. Gla-rich Protein (GRP): A New Player In The Burden Of Vascular Calcification. Journal of Cardiovascular Diseases & Diagnosis. 2016;4(4). doi:10.4172/2329-951710.4172/2329-9517.1000245
Cavaco S, Viegas CSB, Rafael MS, et al. Gla-rich protein is involved in the cross-talk between calcification and inflammation in osteoarthritis. Cell Mol Life Sci. 2016;73(5):1051-65. doi:10.1007/s00018-015-2033-9
Viegas CSB, Simes DC. New Perspectives for the Nutritional Value of Vitamin K in Human Health. Journal of Nutritional Disorders & Therapy. 2016;6(3). doi:10.4172/2161-050910.4172/2161-0509.1000192
2015
Richard N, Engrola S, Palma PS, Simes DC, Conceição LEC. Assessment of protein digestive capacity and metabolic utilisation during ontogeny of Senegalese sole larvae: A tracer study using in vivo produced radiolabelled polypeptide fractions. Aquaculture. 2015;441:35 - 44. doi:10.1016/j.aquaculture.2015.02.003
Viegas CSB, Rafael MS, Enriquez JL, et al. Gla-rich protein acts as a calcification inhibitor in the human cardiovascular system. Arterioscler Thromb Vasc Biol. 2015;35(2):399-408. doi:10.1161/ATVBAHA.114.304823
Viegas CSB, Rafael MS, Enriquez JL, et al. Gla-rich protein (GRP) is a new player in mineralization-competence of extracellular vesicles involved in vascular calcification. Journal of Vascular Research. 2015;52(1):1 - 88. doi:10.1159/000433498
2014
Viegas CSB, Herfs M, Rafael MS, et al. Gla-rich protein is a potential new vitamin K target in cancer: evidences for a direct GRP-mineral interaction. Biomed Res Int. 2014;2014:340216. doi:10.1155/2014/340216
Rafael MS, Cavaco S, Viegas CSB, et al. Insights into the association of Gla-rich protein and osteoarthritis, novel splice variants and γ-carboxylation status. Mol Nutr Food Res. 2014;58(8):1636-46. doi:10.1002/mnfr.201300941
Cavaco S, Williamson MK, Rosa J, et al. Teleost fish osteocalcin 1 and 2 share the ability to bind the calcium mineral phase. Fish Physiol Biochem. 2014;40(3):731-8. doi:10.1007/s10695-013-9880-9
2013
Viegas CSB, Simes DC, Williamson MK, et al. Sturgeon osteocalcin shares structural features with matrix Gla protein: evolutionary relationship and functional implications. J Biol Chem. 2013;288(39):27801-11. doi:10.1074/jbc.M113.450213
2012
Oliveira DV, Silva TS, Cordeiro OD, Cavaco SI, Simes DC. Identification of proteins with potential osteogenic activity present in the water-soluble matrix proteins from Crassostrea gigas nacre using a proteomic approach. ScientificWorldJournal. 2012;2012:765909. doi:10.1100/2012/765909
2010
Viegas CSB, Conceição N, Fazenda C, Simes DC, M. Cancela L. Expression of Gla-rich protein (GRP) in newly developed cartilage-derived cell cultures from sturgeon ( Acipenser naccarii ). Journal of Applied Ichthyology. 2010;26(2):214 - 218. doi:10.1111/jai.2010.26.issue-210.1111/j.1439-0426.2010.01408.x
2009
Viegas CSB, Cavaco S, Neves PL, et al. Gla-rich protein is a novel vitamin K-dependent protein present in serum that accumulates at sites of pathological calcifications. Am J Pathol. 2009;175(6):2288-98. doi:10.2353/ajpath.2009.090474
Roberto VP, Cavaco S, Viegas CSB, et al. Matrix Gla protein in turbot (Scophthalmus maximus): Gene expression analysis and identification of sites of protein accumulation. Aquaculture. 2009;294(3-4):202 - 211. doi:10.1016/j.aquaculture.2009.06.020
2008
Viegas CSB, Simes DC, Laizé V, Williamson MK, Price PA, M. Cancela L. Gla-rich protein (GRP), a new vitamin K-dependent protein identified from sturgeon cartilage and highly conserved in vertebrates. J Biol Chem. 2008;283(52):36655-64. doi:10.1074/jbc.M802761200
2006
Ortiz-Delgado JB, Simes DC, Viegas CSB, Schaff BJ, Sarasquete C, M. Cancela L. Cloning of matrix Gla protein in a marine cartilaginous fish, Prionace glauca: preferential protein accumulation in skeletal and vascular systems. Histochem Cell Biol. 2006;126(1):89-101. doi:10.1007/s00418-005-0125-6