MODEL-EDC - Workshop
Monday, November 22, 2021 to Tuesday, November 23, 2021
Course Description
This workshop is funded as a Foresight Workshop by Euromarine with the following aims:
1. Map current assays and models of risk assessment and monitoring for Endocrine-disrupting chemicals (EDCs, that interfere with the endocrine systems), in vertebrate and invertebrate marine organisms
2. Discuss how predictive and representative current models are (mostly freshwater species) for the marine organisms, considering their great taxa diversity, their interconnection and possible biomagnification of EDC/toxicant effects across the food chain.
3. Assess the gaps in knowledge while taking into consideration exposure to single chemicals or complex mixes from a biological and chemical perspective
Format
A first version of this workshop will be run ONLINE between 22 and 23 of November 2021 and will include two public sessions (for up to 50 inscribed participants, free of charge) with lectures from top international experts in Endocrine Disruption and Pollutant Monitoring Programs.
It will also include restricted working group discussions between these experts in ecotoxicology and endocrine disruption to review the current state of the art in terms of the EDC threats to marine organisms, current assays for evaluating and predicting risks of exposure and their limitations / applicability to the marine biosphere. This network will formulate recommendations for future actions.
REGISTRATION
Since the workshop is funded by Euromarine, registration for the open parts of the workshop (lectures) is free of charge, so all registered participants (limit of 50) can participate, on a basis of first-come, first-served.
20 participations will be reserved for students (preferentially PhD and early-career scientists). Please register here and we will respond if you were accepted, by November 10.
For registrations, we will ask for your personal data, affiliation and a short text (up to 100 words) explaining your motivation to attend (if we exceed the limit of registrations, replacement of any released or extra places can be subjected to a simple selection based on the motivation text).
Pre-requisites
Participants are expected to have general background in marine biology, pollution monitoring or related fields.
Agenda
Intended Audience
Scientists and students interested in the risk assessment of environmental pollutants and monitoring of adverse effects (namely endocrine disruption) in marine organisms.
Scientific Organisation
Instructors
Adam Lillicrap
Norwegian Institute for Water Research (NIVA)
NIVA GLP Manager and Research Manager for Ecotoxicology&Risk Assessment with >20yrs experience in project managing and directing regulatory ecotoxicity tests. He is a EUROTOX Registered Toxicologist (ERT) involved in many international committees/expert working groups and NW representative for OECD validation management group for ecotoxicity tests and ISO Water Quality test standards. Interests involve understanding how chemicals are regulated within environmental contexts and how to influence regulatory policy decisions.
ALICE BAYNES
Brunel University London, UK
Alice is a Lecturer in Environmental Sciences, research group leader, and member of Brunel University London’s Centre for Pollution Research and Policy. She has a BSc in Marine Biology from University of Hull and PhD in Environmental Toxicology from Brunel University London. She has >15 years research experience in the field of aquatic ecotoxicology and endocrine disruption. Currently her focus is on comparative endocrinology in molluscs with an aim to support ecotoxicology/regulatory testing.
Carlie LaLone
US Environmental Protection Agency (US EPA), Great-Lakes Toxicology and Ecology Division, Duluth, MN, USA
CL has a PhD in Genetics and is bioinfomaticist at USEPA focused at understanding toxic effects of chemicals across species using predictive computational methods. She has developed the Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) tool, that uses genetic information to identify species similarities for binding different classes of chemicals. With this work she received the prestigious Presidential Early Career Award for Scientists and Engineers (PECASE).
Christophe Minier
Ifremer Nantes, France
Christophe Minier is professor at the University of Le Havre - Normandy. He carries out his research on the mechanisms and effects of endocrine disruptors, particularly in molluscs and fish. He leads the European research programme RedPol. He is Chairman of the French Committee on chemical substances covered by the REACH and CLP regulations. C. Minier is an expert in the national committees on chemical substances, endocrine disruptors, plant protection products, effects on coral reefs.
Gerald (Gary) Ankley
US Environmental Protection Agency (US EPA), Great-Lakes Toxicology and Ecology Division, Duluth, MN, USA
He is a Senior Research Toxicologist at USEPA and Adjunct Professor at Univ. Minnesota with >30 yrs experience in aquatic toxicity testing and wildlife/predictive ecological risk assessment for EDCs. He has >400 papers and book chapters and represents USEPA in national & international efforts in chemical regulation/risk assessment like WHO or OECD. He received >50 Science&Technology Achievement Awards (Science Advisory Board), the SETAC Founders Award (2008) and the Presidential Rank Award from the White House (2017).
Henrik Holbech
University of Southern Denmark (SDU), Department of Biology, Denmark
He is a PhD in Ecotoxicology and Associate Professor at SDU with > 20 years research on EDCs in aquatic species and biomarkers to include in EDC test guidelines. He led the OECD validations of “the Fish Sexual development Test” (2006-2011). He coordinates H2020 project ERGO on new endpoints to assess thyroid hormone system disruption in vertebrates and better use of data between human health and env. EDC assessment. He is the DK representative at the ECHA ED expert group, OECD VMG-Eco and OECD ED testing/assessment advisory group EDTA AG.
Ibon Cancio
Plentzia Marine Station (PiE-UPV/EHU), University of the Basque Country (UPV/EHU), EMBRC-Spain
He is a PhD coordinating the MSc degree in Environmental Contamination & Toxicology at the Univ. of the Basque Country for 10 years and a researcher of the consolidated research group of Cell Biology & Environ. Toxicol. At Plentzia Marine Station, with participation in >50 research projects. His research focuses on the cell/molecular biology of fish sex differentiation and molecular biomarkers of endocrine disruption. Publications: 9 book chapters, 61 articles in ISI-indexed journals and 8 in national ones. H-index=24. He is director of the Spanish node of the European RI EMBRC.
Ioanna Katsiadaki
Cefas (Centre for Environment, Fisheries and Aquaculture Science) Weymouth Laboratory, UK
She is a Principal Fish Physiologist/Endocrinologist at CEFAS Weymouth Lab, honorary Professor at Univ.Exeter and developer of the first assay for an androgen induced protein (stickleback spiggin) subsequently used for chemical screening and environmental monitoring. She is a UK representative in the OECD Fish Expert Group and one of the theme leaders of the UK-Japan cooperation on EDCs. She is advisor of the UK Environment Agency on issues related to EDCs in aquatic environments and authored > 100 papers and book chapters.
JOACHIM STURVE
Department of Biological & Environmental Sciences, University of Gothenburg, Sweden
JS is a professor and expert in ecotoxicology at Univ. Gothenburg, focusing on molecular/biochemical subcellular effects of chemicals/nanoparticles, including biomarkers of cellular antioxidant defence system and oxidative stress in different cellular pathways. Most research is focused on the effects of EDCs in different fish models both in vivo and in vitro. JS is also involved in aquatic environmental monitoring through his work with national monitoring campaigns and organisations such as ICES and HELCOM.
JOHN PAUL BIGNELL
Cefas (Centre for Environment, Fisheries and Aquaculture Science) Weymouth Laboratory, UK
JB is an aquatic animal health pathologist and principal investigator for marine fish diseases under the UK Clean Seas Environmental Monitoring Programme. He supports the investigation of infectious diseases and the biological effects of contaminants and is a member of the UK Biological Effects of Contaminants in Marine Environment (BECME) working group, and the ICES Expert Working Group on the Biological Effects of Contaminants (WGBEC). John’s research focuses on the identification of causal links between toxicologic liver cancer and contaminants in the marine environment.
Lisa Baumann
University of Heidelberg, Germany
She is an Ecotoxicologist and Group Leader at the Univ. Heidelberg specialized in aquatic toxicology with focus on endocrine effects, hepatotoxicity and immunotoxicity in fish, mainly using zebrafish developmental studies and histopathology. She is regularly recruited as specialist for working groups, contract work and workshops. She is co-PI of the EU research projects “ERGO” and “iFEDT” focused on the implementation of thyroid-sensitive endpoints of fish into existing test guidelines for endocrine disruptors.
I have a PhD in Mol.Biology and am an auxiliary researcher at UAlg, teaching Biology and Metagenomics. My research focus on the diversity, roles and disruption of fish hormone systems by pollutants, using in vitro/in vivo assays and OMICs, mainly applied to EDC risks, aquaculture and food safety, and on the diversity and spreading of microbes in the marine environment and organisms. I was the PI of project E2SCALE (Pt) on non-invasive EDC risk assessment using fish scales and GalPub (Pt, fish reproduction), published 48 articles, am part of the AIEC (Iberian Comparative Endocrinology) board...Read more
PHILIPP ANTCZAC
Center for Molecular Medicine Cologne CMMC, University of Cologne, Germany
He is a computational biologist specialising in utilising data driven approaches to understanding biological questions and straddles the space between biomedical and (eco)toxicological fields. He has experience in all major OMICs techniques, their integration, and statistical analysis. He has represented the UK at several OECD Working groups to establish computational tools in regulation and co-developed several key frameworks within ecotoxicology. He has published 40+ articles and has an h-index of 22.
Peter Matthiessen
Independent Consultant in Ecotoxicology
He has >50 years research experience in aquatic (freshwater and marine) ecotoxicology and is specialised in endocrine disruption (ED), being one of the pioneers discovering that tributyltin antifouling paints caused masculinisation in molluscs and far-reaching effects on marine invertebrates, and studying feminisation of marine fish by sewage discharges to estuaries. He has published > 150 papers and reports and until recently was a member of the UK Hazardous Substances Advisory Committee.
RON VAN DER OOST
Waternet Water Cycle Institute, Amsterdam, The Netherlands
Ron van der Oost is a European Registered Toxicologist, working at the Waternet Water Cycle Institute. He got his PhD at the Molecular Toxicology Division of the VU University of Amsterdam, on a project assessing the environmental quality of inland waters with fish biomarkers. At present he bridges gaps between scientific knowledge and practical application of bioanalytical tools to assess environmental and human health with the Smart Integrated Monitoring strategy (SIMONI).
STEVEN BROOKS
Norwegian Institute for Water Research, NIVA, Norway
He is a Senior Researcher in Ecotoxicology at NIVA Norway with 20 years of research experience in 1) the bioavailability of environment chemicals to aquatic organisms; 2) the development of biomarkers of pollution exposure effects; 3) monitoring biological effects of coastal/offshore produced water discharges in the marine environment, 4) The application of bioassays for risk assessment of environmental chemicals. He is co-chair of the ICES working group on the biological effects of contaminants (WGBEC).
THOMAS KNIGGE
CNRS Stress Environnementaux et BIOsurveillance des milieux aquatiques (UMR-I 02 SEBIO), Université le Havre, France
TK has a PhD in molecular stress physiology of molluscs, arthropods and fish, post-doc experience on proteomics in ecotoxicology at RF-Akvamiljø in Norway (editing a special issue of PROTEOMICS in marine organisms) and is now a senior lecturer and researcher comprises endocrine disruption in marine and freshwater mollusks and neuroendocrinology of crustaceans with their unique endocrine system.
TIPHAINE MONSINJON
Environmental Stress and Aquatic Biomonitoring (SEBIO), University of Le Havre Normandy, France
She has a PhD in Immunology (Rouen University) and post-doc experience in proteomics signatures of Mytilus edulis exposed to environmental pollutants at RF-Akvamiljø in Norway and Le Havre University, where she is a senior lecturer and scientist. She has specialised in fish immunology focussing on the cross-talk between the immune and the endocrine system. She is particularly interested in how steroid sex hormones act on thymic plasticity in fish, both in an ecological and ecotoxicological context.
Venue
Online (via zoom)
