PhD Thesis Presentation of Susana Rodrigues
Our PhD student, Susana Rodrigues from Marine Molecular Bioengineering group, will present and defend her thesis about “Development of polysaccharide-based carriers for pulmonary tuberculosis therapy”.
The defense will be supervised by Ana Grenha (CCMAR) and the juries will be Maria Leonor Quintais Cancela da Fonseca, Maria Luisa González Rodríguez, António José Almeida, Gabriela Araújo da Silva, and Rui Mariano Sousa da Cruz.
Friday | December 20 | 14:30 pm
Anfiteatro Teresa Gamito | Building 1 | Gambelas Campus
Brief summary of Susana thesis:
Tuberculosis remains a deadly pathology and new therapeutic strategies are demanded. Considering that the lung is the primary site of infection, direct lung delivery of antibiotics is an interesting and effective approach. The strategy requires developing carriers with aerodynamic properties ensuring drug delivery in the alveoli, where bacteria are hosted by macrophages. Inhalable spray-dried microparticles with suitable aerodynamic properties to reach the alveoli are proposed with a composition based on chondroitin sulphate or k-carrageenan.