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Filtros: Autor is Cancela, M. Leonor  [Clear All Filters]
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Divisato G, Formicola D, Esposito T, et al. ZNF687 Mutations in Severe Paget Disease of Bone Associated with Giant Cell Tumor. Am J Hum Genet. 2016;98(2):275-86. doi:10.1016/j.ajhg.2015.12.016
Tarasco M, Cordelières FP, M. Cancela L, Laizé V. ZFBONE: An ImageJ toolset for semi-automatic analysis of zebrafish bone structures. Bone. 2020;138:115480. doi:10.1016/j.bone.2020.115480
Fernández I, Vijayakumar P, Marques C, M. Cancela L, Gavaia P, Laizé V. Zebrafish vitamin K epoxide reductases: expression in vivo, along extracellular matrix mineralization and under phylloquinone and warfarin in vitro exposure. Fish Physiology and Biochemistry. 2015;41(3):745-759. doi:10.1007/s10695-015-0043-z
Silva IAL, Varela D, M. Cancela L, Conceição N. Zebrafish optineurin: genomic organization and transcription regulation. Genome. 2022;65(10):513 - 523. doi:10.1139/gen-2022-0019
Tarasco M, Laizé V, Cardeira J, M. Cancela L, Gavaia P. The zebrafish operculum: A powerful system to assess osteogenic bioactivities of molecules with pharmacological and toxicological relevance. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology. 2017;197:45 - 52. doi:10.1016/j.cbpc.2017.04.006
Santos JMA, Laizé V, Gavaia PJ, Conceição N, M. Cancela L. Zebrafish Models to Study Ectopic Calcification and Calcium-Associated Pathologies. International Journal of Molecular Sciences. 2023;24(4):3366. doi:10.3390/ijms24043366
Vitorino M, Conceição N, M. Cancela L. Zebrafish (Danio rerio, Hamilton-Buchanan, 1822) as a model to study bone diseases associated with Rett syndrome. Journal of Applied Ichthyology. 2018;34(2):489 - 500. doi:10.1111/jai.13667
Adrião A, Conceicão N, Gavaia P, M. Cancela L. Zebrafish as a model to study craniofacial phenotypes related to human MEF2C mutations. European Journal of Clinical Investigation. 2013;43:97 - 106. doi:10.1111/eci.2013.43.issue-s110.1111/eci.12088
Tarasco M, Martins G, Gavaia PJ, Bebianno MJ, M. Cancela L, Laizé V. ZEB316: A Small Stand-Alone Housing System to Study Microplastics in Small Teleosts. Zebrafish. 2020;17(1):18-26. doi:10.1089/zeb.2019.1801
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Marques C, Roberto VP, Granadeiro L, et al. The xenobiotic sensor PXR in a marine flatfish species ( Solea senegalensis ): Gene expression patterns and its regulation under different physiological conditions. Marine Environmental Research. 2017;130:187-199. doi:10.1016/j.marenvres.2017.07.021
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Granadeiro L, Dirks RP, Ortiz-Delgado JB, et al. Warfarin-exposed zebrafish embryos resembles human warfarin embryopathy in a dose and developmental-time dependent manner – From molecular mechanisms to environmental concerns. Ecotoxicology and Environmental Safety. 2019;181:559 - 571. doi:10.1016/j.ecoenv.2019.06.042
Fernández I, Santos A, M. Cancela L, Laizé V, Gavaia P. Warfarin, a potential pollutant in aquatic environment acting through Pxr signaling pathway and γ-glutamyl carboxylation of vitamin K-dependent proteins. Environmental Pollution. 2014;194:86-95. doi:10.1016/j.envpol.2014.07.015
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M. Cancela L, Marie PJ, Le Boulch N, Miravet L. Vitamin D3 3 beta sulfate has less biological activity than free vitamin D3 during pregnancy in rats. Biol Neonate. 1985;48(5):274-84.
Bensimon-Brito A, M. Cancela L, Huysseune A, Witten PEckhard. Vestiges, rudiments and fusion events: the zebrafish caudal fin endoskeleton in an evo-devo perspective. Evol Dev. 2012;14(1):116-27. doi:10.1111/j.1525-142X.2011.00526.x
Tiago DM, M. Cancela L, Aureliano M, Laizé V. Vanadate proliferative and anti-mineralogenic effects are mediated by MAPK and PI-3K/Ras/Erk pathways in a fish chondrocyte cell line. FEBS Lett. 2008;582(9):1381-5. doi:10.1016/j.febslet.2008.03.025
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Fernández I, Cardeira J, Granadeiro L, Gavaia P, Laizé V, M. Cancela L. The use of in vivo imaging tools in zebrafish for drug discovery for bone development and homeostasis. Laboratory Animals. 2015;49:26 - 94. doi:10.1177/0023677215609551
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Milan M, Coppe A, Reinhardt R, et al. Transcriptome sequencing and microarray development for the Manila clam, Ruditapes philippinarum: genomic tools for environmental monitoring. BMC Genomics. 2011;12:234. doi:10.1186/1471-2164-12-234
Varela D, Conceição N, M. Cancela L. Transcriptional regulation of human T-box 5 gene (TBX5) by bone- and cardiac-related transcription factors. Gene. 2021;768:145322. doi:10.1016/j.gene.2020.145322
Marques CL, M. Cancela L, Laizé V. Transcriptional regulation of gilthead seabream bone morphogenetic protein (BMP) 2 gene by bone- and cartilage-related transcription factors. Gene. 2016;576(1 Pt 2):229-236. doi:10.1016/j.gene.2015.10.005
Fazenda C, Conceição N, M. Cancela L. Transcription factors from Sox family regulate expression of zebrafish Gla-rich protein 2 gene. Gene. 2015;572(1):57-62. doi:10.1016/j.gene.2015.06.079
Parisi M, M. Cancela L. Time course studies on phosphate transfer in frog urinary bladder. Kidney Int. 1988;33(1):58-63.
Cavaco S, Williamson MK, Rosa J, et al. Teleost fish osteocalcin 1 and 2 share the ability to bind the calcium mineral phase. Fish Physiol Biochem. 2014;40(3):731-8. doi:10.1007/s10695-013-9880-9
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Viegas CSB, Simes DC, Williamson MK, et al. Sturgeon osteocalcin shares structural features with matrix Gla protein: evolutionary relationship and functional implications. J Biol Chem. 2013;288(39):27801-11. doi:10.1074/jbc.M113.450213
Frazão C, Simes DC, Coelho R, et al. Structural evidence of a fourth Gla residue in fish osteocalcin: biological implications. Biochemistry. 2005;44(4):1234-42. doi:10.1021/bi048336z
Laizé V, Rosa JT, Tarasco M, M. Cancela L. Status, challenges, and perspectives of fish cell culture - Focus on cell lines capable of in vitro mineralization. In: Elsevier; 2022:381 - 404. doi:10.1016/B978-0-12-822273-7.00004-5